Which of the following activities would place an animal in category E? D The federally mandated search for alternatives helps to fulfill the requirement set forth in the AWA policies to consider alternatives to procedures that may cause more than momentary pain or distress. B. AAALAC International accreditation is recognized around the world as a symbol of high quality animal care and use for research, teaching and testing, as well as promoting animal welfare. Along with meeting all applicable local and national regulations, AAALAC accredited institutions must also demonstrate that they are achieving the standards outlined in the Guide for the Care and Use of Laboratory Animals (National Research Council, 1996). A change in the principal investigator The mandibular vein, lateral saphenous vein, and retro-orbital sinus are acceptable survival sampling sites. Which of the following are NOT allowed by USDA? Which Public Health Service (PHS) organization is responsible for monitoring organizational compliance with PHS Policy? A. Which of the following organizations must comply with the PHS Policy when utilizing vertebrate animals for research, teaching, or testing? Driving in the summer, winter, or rainy season may be to blame for the unpleasant odor inside the car. Accreditation standards further require hose organizations that accept Public Health Service (PHS) or National Science Foundation (NSF) funding. B. The Council conducts on-site visits and extensive evaluations, and provides ongoing advice to help organizations achieve and maintain accreditation. Let us have a look at your work and suggest how to improve it! B. A. Non-survival surgery is surgery in which the animal is allowed to regain consciousness after the surgery. Submit a report to OLAW or USDA. Which of the following sets of IACUC members are required by the AWA and/or PHS? D. Major non-survival surgery on non-rodent mammals. B. The organization and regulatory agencies only Collecting tail snips from adult rodents for genotyping under local or general anesthesia. Institutions choose to participate in the AAALAC accreditation program for a variety of reasons. All of the following are mouse strains except: A research mouse will typically consume how much food a day? Some types of changes to an animal protocol can be approved administratively by veterinary verification and consultation. AAALAC International is a private, nonprofit organization that promotes humane treatment of animals in science through a voluntary international accreditation program. The Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching (the Ag Guide) A. D. A change in the analgesic agent administered. A. If the investigator believes the event is due to misuse, mistreatment, or noncompliance, the details of the incident should be reported to the IACUC (or use another reporting method recommended by their organization), so that the incident can be reviewed and investigated (if warranted). C. Intervention must occur to remove an animal from a study, sometimes by euthanizing the animal. All answers are correct. Nonverbal communication is defined as how people communicate with each other without talking or writing. ", Which of the following Guides is best used as a source of guidance for animals used in agricultural research and teaching? AAALAC International standards for accreditation are set forth by the Guide for the Care and Use of Laboratory Animals, established by the U.S. National Research Council in 2011. Which of the following Guides is best used as a source of guidance for animals used in agricultural research and teaching? What is generally a superior anesthesia choice for mice undergoing major surgical procedures? Work bare-handed to prevent loss of tactile sensation caused by disposable gloves. Accreditation by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International has long been trumpeted as being the "gold standard" B. Once a report of mistreatment, misuse, or noncompliance is received, the AWR and PHS Policy require the IACUC to review and investigate the allegations (if warranted). The various behavioral forms that nonverbal communication takes are referred to as nonverbal, Why give alpha blocker before beta blocker in pheochromocytoma. The tail vein in a mouse cannot be used to collect small amounts of blood. A If investigators plan to contract with a commercial enterprise or other entity to produce custom antibodies, whether polyclonal or monoclonal, they must obtain approval from the IACUC. Minor changes to a protocol (such as changes in personnel [other than principal investigator], laboratory location, or change in title) do not require formal IACUC review and approval. A. UsingAAVrh10,Raetal.achievedgreaterefcacyin mice by either increasing the dose via combined route of administration,27 combination of systemic AAVrh10 with . C. Inoculation of recombinant infectious agents into animals C. The Institutional Official in charge of the research program Mice are physiologically unable to vomit, they have no risk for respiratory aspiration of vomitus under anesthesia. B. Check all that apply. Members of the Council are chosen to serve based on their extensive experience in the fields of veterinary medicine, laboratory animal science or animal research, and their commitment to humane animal care and use. Weve got your back. The Council also appoints a roster of ad hoc Consultants/Specialists. Before any use of the animals for the project begins. Treatments under the program may be declined, but enrollment may not. The Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching (the Ag Guide). The three Rs of Russell and Burch stand for what? The IACUC can exempt an animal for scientific reasons. Withhold feed during at least 12 hours following surgery. D. The Office of Laboratory Animal Welfare (OLAW). Which of the following statements concerning euthanasia in neonates is true? Studies in which animals are allowed to die without pain relief. Which of the following sets of IACUC members are required by the AWA and/or PHS? However, agricultural animals used in biomedical research may need to be housed according to the Guide while on study. In the years that followed, AAALAC accredited hundreds of organizations across the United States, raising the benchmark for laboratory animal care to new heights. Assist with writing the basic science portions of a grant application. D. The organization, investigators, animals, and public health and welfare. Having a selective small molecule tool to interrogate this kinase will help demonstrate that CAMKK2 inhibition can be Dose rates (ml/kg) of injectable agents are the same for all common laboratory animal species. A. D Written postoperative care records are kept for individual animals larger than rodents, but written records for groups of rodents are the norm. B. Postoperative analgesia is not generally needed in rodents. B. Sponsors an accreditation program Female mice have how many pairs of nipples? C. While under anesthesia, mice should be monitored for cardiovascular and respiratory function and body temperature. Ambient air is at $25^{\circ} \mathrm{C}$ and $1 \mathrm{~atm}$. But like others in the animal welfare arena, AAALAC endorses the use of animals to advance medicine and science when there are no non-animal alternatives, and when it is done in an ethical and humane way. The 2015 memorandum of understanding between the NIH and NSF also mandates that organizations receiving NSF funding for animal research projects comply with the PHS Policy. D. Laboratory use of recombinant chemical agents for in vitro work. According to the Guide, social animals should be housed in pairs or groups whenever possible. C. 8 percent Despite its importance, only a handful of inhibitors of CAMKK2 have been disclosed. In 1996, AAALAC changed its name to the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International). the anogential distance is greater in the male than in the female. B. Anesthetize or sedate animals to reduce the chances of accidental human needle sticks. This is not intended to be a search to support the necessity or purpose of the research. (1) If, in the opinion of the attending veterinarian, it is inappropriate for certain dogs to exercise because of their health, condition, or well-being, the dealer, exhibitor, or research facility may be exempted from meeting the requirements of this section for those dogs(2) A research facility may be exempted from the requirements of this section if the principal investigator determines for scientific reasons set forth in the research proposal that it is inappropriate for certain dogs to exercise." Which of the following statements is true if an investigator wants to use a human clinical area for animal research? B. Sponsors an accreditation program mandated by U.S. D Organizations receiving funds from PHS agencies are required to comply with the PHS Policy. B. Sponsors a voluntary accreditation program for animal care and use programs. A. AAALAC International 301.696.9626 | www.aaalac.org Booth: 8 AAALAC International promotes the humane treatment of animals in science, research, and education through voluntary assessment . Experimental criteria are the only determinants of the euthanasia method that is acceptable for an animal. C. Sponsors a voluntary accreditation program for animal care and use programs. Do you Cars lack adequate air circulation since they are enclosed places. D. Major. Institutional Animal Care and Use Committee C. Solid bottom cages with contact bedding Your research must comply with the Guide for the Care and Use of Laboratory Animals if: Your institution receives funds from the National Institutes of Health (NIH). Institutions choose to participate in the AAALAC accreditation program for a variety of reasons. Dont worry, you wont be the first person to ask. Which of the following is a role of Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International? A. B. Which of the following is true of the dog exercise program mandated by the AWR? The administration of fluid into the stomach through a feeding needle that is inserted into the mouth and threaded down the esophagus. C. Mice lose body heat rapidly under anesthesia. Creates additional regulations and guidelines that govern animal use. C. Before any use of the animals for the project begins. In Section 3.4, new literature is explored and the assessment of impacts and projected risks is updated for a large number of natural and human systems. Surgery that penetrates and exposes a body cavity or produces substantial physical impairment is defined as what kind of surgery? One book, The Guide for the Care and Use of Laboratory Animals serves as the basic standard represented by AAALAC accreditation. A. Sedation causes vasodilation which helps make the tail vein easier to find. A. A. Ferrets and cats Background. You can help Wikipedia by expanding it. The exercise must take place outside the building. Locked bedroom doors are a common sight in many homes. D. Non-vertebrates, laboratory mice, and laboratory rats. Some of the institutions that have earned AAALAC accreditation include the Sloan-Kettering Cancer Center, St. Jude Children's Research Hospital, The American Red Cross, and the National Institutes of Health. A practicing scientist with experience in animal research, person who is not a scientist, person who is not affiliated with the organization, and public relations specialist. AAALAC International relies on three primary standards used by the Council to evaluate programs: UTSA & AAALAC Accreditation | Date of Inital Accrediation: October 26, 2010. Which of the following is true regarding the IACUCs authority and responsibilities regarding research animal misuse, mistreatment, or noncompliance? D. Animal and Plant Health Inspection Service (APHIS), B According to PHS (2015), OLAW "has responsibility for the general administration and coordination of the Policy, provides specific guidance, instruction, and materials to institutions that must comply with the Policy.". B. Quickly and professionally. To share information with other regulatory agencies D. A change in surgical anesthetic. Determine when emergency IACUC meetings must be scheduled. D. Rodents and rabbits. In the 1950s, the Professional Standards Committee of the Animal Care Panel (ACP), now the American Association for Laboratory Animal Science (AALAS), recognized a need for assuring the general public that laboratory animal research was conducted on a professional level, and that standard procedures were applied. B. Which of the following best describes the purpose of the federally mandated "alternatives search" in an animal protocol? You can get your paper edited to read like this. Which of the following is true about mice in the age range of 1-5 days? In 2016 AAALAC ceased spelling out its acronym in favor of simply using "AAALAC International" as its legal, official name. If an organization accepts PHS funds or is registered with the USDA as a research organization, any protocol suspension must be reported by the Institutional Official to OLAW and USDA. B. Fell free get in touch with us via phone or send us a message. Long-term anesthesia is best achieved by repeat dosages of a short-acting injectable anesthetic cocktail. Which of the following is a role of AAALAC International? The IACUC is charged with ensuring that all personnel involved in animal research are offered enrollment in the organizations occupational health program. A. C. The use of newer surgical techniques that result in less tissue trauma. C. The Guide to Animal Facility Design and Operation A. The fur should A Because they have potential to be used in biological warfare, select agents are given additional regulatory oversight by the CDC. All of the following are practical methods of identifying mice EXCEPT: When producing monoclonal antibodies in vivo, what parameter should be considered? A. Nonaseptic surgical practices are acceptable when it can be shown that mice do not develop postsurgical infections. Accredited Changes in animal ownership and movement of animals between facilities during the postoperative period. Conduct reviews of the animal care and use program on a semiannual basis, Institutional Animal Care and Use Committee. AAALAC Accreditation demonstrates to funding agencies and the general public that the animal care provided goes beyond minimum regulatory requirements. Which of the following represents good practice in oral gavage of mice? Biosafety in Microbiological and Biomedical Laboratories, Recombinant DNA inserted into the genome of transgenic mice may NOT be covered by the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules. D. A goal of sterile technique is to prevent contamination of the surgical site. Surgical procedures should be planned and approved by the IACUC before they are performed. which of the following is true of aaalac international? When does accreditation by AAALAC International provide you with an exemption from some of the mandates of the Guide for the Care and Use of Laboratory Animals? What is a problem that is often encountered with mice housed on wire mesh flooring? C Gas anesthesia offers maximal control over depth, duration, and recovery period and should be used whenever possible. C. Sterile technique is optional for survival surgeries. AAALAC stipulates that accredited institutions observe any and all statutes and governmental regulations which bear upon animal care and use. Which of the following activities would EXCLUDE an animal from USDA category D? D. 5 percent, Because they cannot vomit and are not prone to aspiration pneumonia, which of the following animals should not routinely be fasted prior to surgery? D. If an animal undergoes non-survival surgery, the fur around the surgical site should be clipped and clean instruments should be used. B. The IP injection site is on the animal's right side, close to the midline, in a caudal quadrant of the abdomen. C Category D of the USDA report form applies to " animals upon which experiments, teaching, research, surgery, or tests were conducted involving accompanying pain or distress to the animals and for which appropriate anesthetic, analgesic, or tranquilizing drugs were used. They do not apply to nonrecombinant ones. B. D. The use of computer modeling software to substitute for animal experiments. Investigators should enroll in the local Occupational Health and Safety Program before beginning work with laboratory animals. D Sterile technique is not required for non-survival surgery, but fur clipping and clean instruments are. C. A change in personnel. The name change reflected the organizations recognition and expansion in other countries, and its commitment to enhancing life sciences and quality animal care around the world. D. Written postoperative care records are not necessary, as long as proper care is provided and treatments are administered. C. Applicable federal mandates require the use of aseptic technique for survival surgery in mice. AAALAC International is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. B. Retroorbital blood collection from a mouse performed under anesthesia. The name change reflects the organization's growth in other countries, and its commitment to enhancing life sciences and quality animal care around the world. When animals are used, AAALAC works with institutions and researchers to serve as a bridge between progress and animal well-being. A. Which of the following is true of AAALAC International? A. Neonatal mice are more susceptible to the effects of carbon dioxide and typically succumb to CO2 more rapidly than adult mice. The Council is divided into North American, Pacific Rim and European Sections. If an organization accepts PHS funds or is registered with the USDA as a research organization, any protocol suspension does not have to be reported by the Institutional Official to OLAW and USDA.
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